With all the excitement surrounding the first(ish?) female Doctor, there's lots of cries of misogyny for taking this long to have a female Doctor. This has me curious now. I can't think of too many cases where a character changes sex. Shows I can think of are:
- Doctor Who
- Predestination (Heinlein's All You Zombies adapted to film)
What's the earliest release date of a movie or TV show where a major character changed from male to female or vice versa? For purposes of this, I'd like to exclude hemaphrodites, which just make things confusing.
I'm more interested in permanent changes, because my interest lies in the side effects of such changes, but if there's a particularly good reason to include a temporary change, I'd entertain it. I'd be looking for a transition which occurs during the time frame of the movie/show.