This is The Clone Codes by Patricia & John McKissack
The Goodreads review of the story contains numerous references to clones (duh), clone rights, virtual avatars of various famous abolitionists and a benevolent alien species called "The O":
In the year 2170 an underground abolitionist movement fights for the
freedom of cyborgs and clones, who are treated no better than slaves
The Cyborg Wars are over and Earth has peacefully prospered for more
than one hundred years. Yet sometimes history must repeat itself until
humanity learns from its mistakes. In the year 2170, despite
technological and political advances, cyborgs and clones are treated
no better than slaves, and an underground abolitionist movement is
fighting for freedom. Thirteen-year-old Leanna's entire life is thrown
into chaos when The World Federation of Nations discovers her mom is
part of the radical Liberty Bell Movement.
With the help of some virtual “Custodians” (Ben Franklin & Eleanor
Roosevelt & others), Leanna learns some harsh truths about the world
she lives in.
The entire thing with the O seemed to have been pulled from a cheesy
scifi movie and made the plot way to complex.